It is just crazy when a Bible verse pops up more than once, but recently, I had the same verse pop up 3 different times, in 3 books I was reading!
The message of this verse is that God is holding me in the palms of His hands. He holds me so tight that I am imprinted on his palms. Even when life is topsy-turvy, the future uncertain, and tears are running down my face, I KNOW I am being held by my heavenly Father. That is true comfort!